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Julia Bell

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For the British author, see Julia Bell (author).
Not to be confused with Julie Bell.

Julia Bell
Born(1879-01-28)28 January 1879
Sherwood, Nottinghamshire, England
Died26 April 1979(1979-04-26) (aged 100)
London, England
EducationGirton College, Cambridge; Trinity College, Dublin; London School of Medicine for Women; London School of Medicine for Women (Royal Free Hospital)
Known forStatistical investigations of the inheritance of anomalies and diseases
AwardsWeldon Memorial Prize (1941)
Scientific career
FieldsGenetics eugenics
InstitutionsUniversity College London, Medical Research Council
Academic advisorsKarl Pearson

Julia Bell MA Dubl (1901) MRCS LRCP (1920) MRCP (1926) FRCP (1938)[1] (28 January 1879 – 26 April 1979) was one of the pioneers of eugenics and human genetics.[2][3] Her early career as a statistical assistant to Karl Pearson (1857–1936) marked the beginning of a lifelong professional association with the Galton Laboratory for National Eugenics (renamed the Department of Human Genetics and Biometry in 1966) at University College London. Bell's work as a human geneticist was based on her statistical investigations into the inheritance of anomalies and diseases of the eye, nervous diseases, muscular dystrophies, and digital anomalies.[4]

Biography

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Julia Bell attended Girton College in Cambridge and took the Mathematical Tripos exam in 1901.[5] Because women could not officially receive degrees from Oxford or Cambridge, she was awarded a master's degree at Trinity College, Dublin for her work investigating solar parallax at Cambridge Observatory.[6]

In 1908, she started work at University College London as assistant to Karl Pearson (1857–1936), professor of applied mathematics, director of the Galton Laboratory for National Eugenics at University College, London [7][8] and one of the founders of modern statistics. Bell's predecessor as assistant to Karl Pearson was the mathematician Alice Lee who had resigned due to ill-health.[9]

Bell's position as Assistant to Karl Pearson was funded by Francis Galton's endowment to University College London to support eugenics research.[10] Pearson described the role of his Assistant as "a post well suited to a woman living with her family in London and keen on scientific work" because the Assistant's salary of £100 a year was unattractive to men compared with the annual salary of £250 year paid for the position of Galton Laboratory Research Fellow.[9] Bell's remuneration for her work as Pearson's assistant was equivalent to the pay of a non-academic part-time clerk at this time.[9] Like other women scientists of the period, Bell's early professional life throughout the 1920s was defined by low pay and short-term research contracts.[7] In 1921, Bell was awarded a Fellowship worth £300 p.a. by the Medical Research Council.[11]

In 1914, Karl Pearson had asked Bell to augment the expertise of the Galton Laboratory staff by taking a degree in medicine.[12] Bell's decision to train as a doctor was informed by her own interest in the more observational aspects of the study of heredity.[7] She studied at the London School of Medicine for Women (Royal Free Hospital) which had been the first medical school in Britain to admit women, and the only school to do so until 1886.[13] In the years prior to the outbreak of the First World War, Bell was the only staff member of the Galton Lab who was medically qualified.[11] Bell qualified MRCS LRCP in 1920, was awarded membership of the Royal College of Physicians and made Galton research fellow under the Medical Research Council in 1926, and was elected Fellow of the Royal College of Physicians in 1938, being only the fourth woman to be so elected.[7][8]

Between 1907 and 1925, Bell was employed intermittently in both the Biometric and Galton Laboratories, both of which sat within the Department of Applied Statistics at UCL under the directorshop of Karl Pearson.[11] At the time of Pearson's retirement in 1933, Bell was one of five long-term members of staff who had been in place since 1922, along with Ethel Elderton, Dr. Percy Stocks, Egon Pearson, and Mary Noel Karn.[11] In 1932, Bell had joined the genetics committee of the Medical Research Council and worked as a permanent member of the scientific staff of the Medical Research Council 1933-1944.[14] Her subsequent work led to her receiving the Weldon memorial prize and medal for biometry awarded by Oxford University in 1941. Bell worked within the Galton Laboratory for 57 years, working there from 1908 until her retirement in 1965 at age 86.[1]

Publications

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Julia Bell's early output at the Galton Laboratory included co-authoring "A Statistical Study of Oral Temperatures in School Children with Special Reference to Parental, Environmental and Class Differences" in 1914.[15] The other authors were Mary Hamilton Williams and Karl Pearson. The study compared the temperatures of 4,654 children at different schools in Worcestershire, England, to determine whether conditions like rheumatism and phthisis were hereditary. They concluded that "there is a real and marked difference in temperature between the children of the higher and lower social classes," a difference that they argued was due to poverty and to some extent heredity rather than "home environment" or "nourishment". They continue: "The poor are largely poor because of their defective physique, and the segregation of those with defective physique cannot be obviated, as long as the birth-rate is not directly determined by the physique of the parents."[15]

In 1917 and 1919, Bell published a multi-part series titled A study of the long bones of the English skeleton Part I, Part I: Section II, co-authored with Karl Pearson.[16][17] Other women working at the Galton Laboratory who contributed to this work included: Assistant E. Augusta Jones (formerly Secretary to Francis Galton[18]), Assistant and mathematician Eleanor Pairman, Assistant Mary Seeger, microscopist Marion Radford,[19] Eva Bramley Moore, mathematician Alice Lee, and Assistant Eveline Y. Thomson.[16] The work was part-funded by a donation from Gertrude H. Jones, a former Secretary to the Galton Laboratory.[16] Pearson and Bell's analysis of the skeletal remains of different human populations and primates sought to identify "racial differences in man",[16] informed by the pseudo-science of eugenics originally formulated by Francis Galton whose bequest had funded the Galton Laboratory.[20]

Working as a member of the permanent staff of the Medical Research Council at the Galton Laboratory (renamed the Department of Human Genetics and Biometry in 1966), Julia Bell went on to do pioneering work in documenting the familial nature of many diseases.

Bell wrote most of the sections in the unique series The Treasury of Human Inheritance published by the Galton Laboratory between 1909 and 1956.[21] She was sole or lead author for all sections of Volume II: Nettleship Memorial Volume on Anomalies and Diseases of the Eye (1933), Volume IV: Nervous Diseases and Muscular Dystrophies (1948), and Volume V: On Hereditary Digital Anomalies (1951–58).[22] Bell's "combination of mathematical training, genetic knowledge and clinical expertise yielded numerous important insights into human inheritance first appearing in the Treasury," Harper noted.[23] Julia Bell's Treasury of Human Inheritance "remains a valuable scientific as well as an historical record of the genetics of a range of important inherited disorders."

In 1937, Julia Bell published a landmark article with J. B. S. Haldane which reported a linkage between the genes for colourblindness and haemophilia on the X chromosome.[24] This discovery was a key step toward the mapping of the human genome.

In 1943, Bell co-authored with James Purdon Martin a paper on the link between a form of intellectual disability in children and the X-chromosomes of the parents, with the condition subsequently being named Martin–Bell syndrome.[25][26] It is now known as fragile X syndrome.

Julia Bell's 1951 work 'On Brachydactyly and Symphalangism' in Volume V: On Hereditary Digital Anomalies (1951–58) for The Treasury of Human Inheritance series was foundational for later research into the medical syndrome brachydactyly.[27][28]

Julia Bell kept working actively for many years. At age 82 and still working for the Galton Laboratory, she published "On rubella in pregnancy" in The British Medical Journal.[29][26] She retired at age 86; she kept in touch with genetics until her death at the age of 100.

[edit]

The following Galton Laboratory publications authored or co-authored by Julia Bell are available on the UCL Modern Genetics Collection on Internet Archive. This collection has been made available for historical research purposes. Racist, ableist and classist ideas contained within this material do not reflect the current views of UCL.

The complete set of The Treasury of Human Inheritance including all sections authored or co-authored by Julia Bell is available online at the Wellcome Collection.

References

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  1. ^ a b "Julia Bell | RCP Museum". history.rcplondon.ac.uk. Retrieved 9 February 2024.
  2. ^ Robson, Elizabeth B. (13 September 1979). "Obituary: Julia Bell". Nature. 281 (5727): 163–164. Bibcode:1979Natur.281..163R. doi:10.1038/281163b0.
  3. ^ Greta Jones, 'Bell, Julia (1879–1979)', Oxford Dictionary of National Biography, Oxford University Press, Sept 2004; online edn, Jan 2008 accessed 10 May 2008
  4. ^ "Obituary: Julia Bell". The Lancet. 313 (8126): 1152–1154. 1979. doi:10.1016/s0140-6736(79)91838-5. ISSN 0140-6736.
  5. ^ Ogilvie, Marilyn Bailey and Joy Harvey, The Biographical Dictionary of Women in Science: Pioneering Lives from Ancient Times to the Mid 20th Century Routledge (2000)
  6. ^ Stratton, F.J.M. "The History of the Cambridge Observatories" Annals of the Solar Physics Observatory, Cambridge Vol. I (1949)
  7. ^ a b c d Jones, Greta (2004). "Bell, Julia (1879–1979), geneticist". Oxford Dictionary of National Biography (online ed.). Oxford University Press. doi:10.1093/ref:odnb/38514. Retrieved 6 February 2024. (Subscription or UK public library membership required.)
  8. ^ a b "Julia Bell | RCP Museum". history.rcplondon.ac.uk. Retrieved 6 February 2024.
  9. ^ a b c Love, Rosaleen (1979). "'Alice in Eugenics-Land': Feminism and Eugenics in the scientific careers of Alice Lee and Ethel Elderton". Annals of Science. 36 (2): 145–158. doi:10.1080/00033797900200451. ISSN 0003-3790.
  10. ^ Cain, Joe (24 May 2019). "Eugenics Money at UCL from Francis Galton". Professor Joe Cain. Retrieved 6 February 2024.
  11. ^ a b c d Farrall, Lyndsay Andrew (1969). "The origins and growth of the English eugenics movement 1865-1925 (PhD Thesis, Indiana University, 1969)". UCL Science and Technology Studies.
  12. ^ "La Bell Époque: A Century of Julia Bell (part 1) | RCP Museum". history.rcplondon.ac.uk. Retrieved 26 January 2024.
  13. ^ "LONDON SCHOOL OF MEDICINE FOR WOMEN | London Metropolitan Archives". search.lma.gov.uk. Retrieved 11 February 2024.
  14. ^ "Vignette: pioneering geneticist, Julia Bell (1879-1979)". MDDUS. Retrieved 6 February 2024.
  15. ^ a b Williams, Mary Hamilton; Bell, Julia; Pearson, Karl (1914). A Statistical Study of Oral Temperatures in School Children with Special Reference to Parental, Environmental, and Class Differences. The UCL Institute of Education. Dulau and Co. p. 78.
  16. ^ a b c d Pearson, Karl; Bell, Julia (1917). A study of the long bones of the English skeleton. Part I. The UCL Institute of Education. Cambridge University Press.
  17. ^ Pearson, Karl; Bell, Julia (1919). A study of the long bones of the English skeleton. Part I, section II. The UCL Institute of Education. Cambridge University Press.
  18. ^ "Galton Papers, GALTON/2/10/9/20". UCL Special Collections. Retrieved 6 February 2024.
  19. ^ Pendleton, Mark (2001). A place of teaching and research: University College London and the origins of the research university in Britain 1890-1914 (Doctoral thesis). UCL (University College London).
  20. ^ UCL (18 November 2021). "Our Early History". Statistical Science. Retrieved 6 February 2024.
  21. ^ "Treasury of human inheritance / edited by Karl Pearson, R.A. Fisher, L.S. Penrose". Wellcome Collection. Retrieved 6 February 2024.
  22. ^ "Treasury of Human Inheritance (1909-1958) | Eugenics Laboratory". Professor Joe Cain. Retrieved 6 February 2024.
  23. ^ Harper, P. S. (2005). "Julia Bell and the Treasury of Human Inheritance". Human Genetics. 116 (5): 422–432. doi:10.1007/s00439-005-1264-5. PMID 15735957.
  24. ^ Bell, J.; Haldane, J. B. S. (1937). "The Linkage between the Genes for Colour-Blindness and Haemophilia in Man". Proceedings of the Royal Society B. 123 (831): 119–150. Bibcode:1937RSPSB.123..119B. doi:10.1098/rspb.1937.0046.
  25. ^ Martin, J. P. & Bell, J. (1943). "A pedigree of mental defect showing sex-linkage". J. Neurol. Psychiatry. 6 (3–4): 154–157. doi:10.1136/jnnp.6.3-4.154. PMC 1090429. PMID 21611430.
  26. ^ a b King, Jesse. "Julia Bell (1879-1979) | Embryo Project Encyclopedia". Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. ISSN 1940-5030. Retrieved 6 February 2024.
  27. ^ Temtamy, Samia A.; Aglan, Mona S. (2008). "Brachydactyly". Orphanet Journal of Rare Diseases. 3 (1): 15. doi:10.1186/1750-1172-3-15. ISSN 1750-1172. PMC 2441618. PMID 18554391.
  28. ^ Pitt, P.; Williams, I. (1985). "A new brachydactyly syndrome with similarities to Julia Bell types B and E". Journal of Medical Genetics. 22 (3): 202–204. doi:10.1136/jmg.22.3.202. ISSN 0022-2593. PMC 1049425. PMID 4009643.
  29. ^ Bell, Julia (14 March 1959). "On Rubella in Pregnancy". British Medical Journal. 1 (5123): 686–688. doi:10.1136/bmj.1.5123.686. ISSN 0007-1447. PMC 1993148. PMID 13629090.
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